60 days in Caribbean, Mexico, Central America & South America Itinerary

60 days in Caribbean, Mexico, Central America & South America Itinerary

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1
Nassau, Bahamas
— 3 nights
2
Havana, Cuba
— 4 nights
3
Mexico City, Mexico
— 5 nights
4
Granada, Nicaragua
— 1 night
5
La Fortuna de San Carlos, Costa Rica
— 4 nights
6
Manuel Antonio, Costa Rica
— 4 nights
7
Panama City, Panama
— 1 night
8
San Andres Island, Colombia
— 2 nights
9
Cartagena, Colombia
— 3 nights
10
Los Roques National Park, Venezuela
— 1 night
11
Quito, Ecuador
— 3 nights
12
Cusco, Peru
— 4 nights
13
Uyuni, Bolivia
— 1 night
14
San Pedro de Atacama, Chile
— 3 nights
15
San Carlos de Bariloche, Argentina
— 4 nights
16
Punta del Este, Uruguay
— 2 nights
17
Ciudad Del Este, Paraguay
— 1 night
18
Florianopolis, Brazil
— 4 nights
19
Brasilia, Brazil
— 3 nights

3
nights
Nassau, Bahamas

Nassau ©
On a trip to Nassau you can immerse yourself in a dynamic city atmosphere or spend your days lazing on the soft golden sands.
You'll explore the less-touristy side of things at John Watling's Distillery and Pirates of Nassau Museum. Escape the urban bustle at Speed Boats Tours and Cable Beach. Next up on the itinerary: steep yourself in history at Queen's Staircase and get up close and personal with brilliant marine life at Marine Habitat at Atlantis.

To find other places to visit, more things to do, ratings, and more tourist information, read our Nassau trip itinerary maker site.

Lyon, France to Nassau is an approximately 17-hour flight. Traveling from Lyon to Nassau, you'll gain 6 hours due to the time zone difference. When traveling from Lyon in September, plan for a bit warmer days in Nassau, with highs around 38°C, while nights are much warmer with lows around 29°C. Wrap up your sightseeing on the 4th (Fri) early enough to travel to Havana.

Things to do in Nassau

Parks · Outdoors · Zoos & Aquariums

Side Trip

Marine Habitat at Atlantis
Find places to stay Sep 1 — 4:
Highlights from your plan
Cable Beach ©
Cable Beach
John Watling's Distillery ©
John Watling's Distillery
Pirates of Nassau Museum ©
Pirates of Nassau Museum

4
nights
Havana, Cuba

Havana ©
Cuba's capital and major commercial center, Havana manages to be very old and very modern at the same time.
Get in touch with nature at Playa Paraiso and Sirena Beach. Revolution Plaza Havana and Plaza de San Francisco will appeal to history buffs. There's much more to do: steep yourself in history at Finca Vigía, make a trip to Plaza de la Catedral, contemplate in the serene atmosphere at Havana Cathedral, and admire the masterpieces at Museu Nacional de Belas Artes de Cuba.

For reviews, ratings, and tourist information, you can read our Havana trip builder site.

You can fly from Nassau to Havana in 4.5 hours. Traveling from Nassau in September, Havana is little chillier at night with lows of 26°C. Wrap up your sightseeing on the 8th (Tue) early enough to travel to Mexico City.

Things to do in Havana

Outdoors · Historic Sites · Beaches

Side Trip

Cayo Largo
Find places to stay Sep 4 — 8:
Highlights from your plan
Playa Paraiso ©
Playa Paraiso
Sirena Beach ©
Sirena Beach
Revolution Plaza Havana ©
Revolution Plaza Havana

5
nights
Mexico City, Mexico

Mexico City ©
Breathtakingly large, Mexico City provides a home for almost 9 million people living in nearly 1,700 distinct neighborhoods.
Museo Memoria y Tolerancia and Rosary Chapel (Capilla del Rosario) are good opportunities to explore the local culture. Museo De la Tortura and Museo Soumaya will appeal to museum buffs. Get out of town with these interesting Mexico City side-trips: Puebla (Museo de la Evolucion Puebla (Museum of Evolution Puebla) & Templo de San Francisco). There's much more to do: pause for some serene contemplation at Iglesia de Nuestra Senora de Guadalupe, explore the historical opulence of Chapultepec Castle, contemplate the long history of Metropolitan Cathedral (Catedral Metropolitana), and brush up on your military savvy at Museo del Ejercito y Fuerza Aerea Mexicanos Bethlemitas.

To find more things to do, maps, photos, and tourist information, use the Mexico City holiday planner.

Traveling by flight from Havana to Mexico City takes 6.5 hours. The time zone difference moving from Cuba Standard Time (CST) to Central Standard Time (CST) is minus 1 hour. In September, Mexico City is slightly colder than Havana - with highs of 26°C and lows of 16°C. Finish up your sightseeing early on the 13th (Sun) so you can travel to Granada.

Things to do in Mexico City

Historic Sites · Museums · Neighborhoods

Side Trip

Puebla
Find places to stay Sep 8 — 13:
Highlights from your plan
Museo Memoria y Tolerancia ©
Museo Memoria y Tolerancia
Rosary Chapel (Capilla del Rosario) ©
Rosary Chapel (Capilla del Rosario)

1
night
Granada, Nicaragua

Granada ©
The lakeside city of Granada has the look and feel of a historically important economic and political center, with grand colonial architecture, a unified look, and many cultural attractions.
Start off your visit on the 14th (Mon): pause for some serene contemplation at Catedral de Granada, take in the architecture and atmosphere at Iglesia de La Merced, and then step off the mainland to explore Islets of Granada.

To see where to stay, more things to do, traveler tips, and tourist information, read Granada trip builder website.

You can fly from Mexico City to Granada in 7 hours. Another option is to drive. Finish your sightseeing early on the 14th (Mon) to allow enough time to drive to La Fortuna de San Carlos.

Things to do in Granada

Historic Sites · Nature · Parks
Find places to stay Sep 13 — 14:
Highlights from your plan
Catedral de Granada ©
Catedral de Granada
Iglesia de La Merced ©
Iglesia de La Merced
Islets of Granada ©
Islets of Granada

4
nights
La Fortuna de San Carlos, Costa Rica

La Fortuna de San Carlos ©
Set against the backdrop of the imposing Arenal Volcano, La Fortuna de San Carlos offers visitors a chance to explore diverse natural landscapes and sample some delicious local produce.
Get in touch with nature at Off-Road Tours and Canyoning & Rappelling Tours. Eschew the tourist crowds and head to Rio Chollin and Arenal Natura Ecological Park. There's lots more to do: take a tour by water with Boat Tours & Water Sports, relax and rejuvenate at Tabacon Hot Springs, and take in the natural beauty of Ecotermales Fortuna.

To find reviews, other places to visit, more things to do, and tourist information, you can read our La Fortuna de San Carlos online vacation planner.

Drive from Granada to La Fortuna de San Carlos in 5 hours. Alternatively, you can do a combination of shuttle and bus; or take a bus. Finish your sightseeing early on the 18th (Fri) so you can drive to Manuel Antonio.

Things to do in La Fortuna de San Carlos

Parks · Nature · Outdoors
Find places to stay Sep 14 — 18:
Highlights from your plan
Tabacon Hot Springs ©
Tabacon Hot Springs
Arenal Natura Ecological Park ©
Arenal Natura Ecological Park
Rio Chollin ©
Rio Chollin

4
nights
Manuel Antonio, Costa Rica

Manuel Antonio ©
The rainforest meets the sea at Manuel Antonio National Park, a small but scenic natural preserve on the west coast of Costa Rica.
Get in touch with nature at Playa Biesanz and Zipline. Take a break from Manuel Antonio with a short trip to Canyoning & Rappelling Tours in Jaco, about 1h 30 min away. Next up on the itinerary: get a dose of the wild on a nature and wildlife tour and paddle through the water with a kayaking and canoeing tour.

To find more things to do, traveler tips, maps, and tourist information, go to the Manuel Antonio road trip tool.

You can drive from La Fortuna de San Carlos to Manuel Antonio in 4.5 hours. Alternatively, you can take a shuttle; or take a bus. Wrap up your sightseeing on the 22nd (Tue) to allow time to travel to Panama City.

Things to do in Manuel Antonio

Outdoors · Tours · Adventure

Side Trip

Jaco
Find places to stay Sep 18 — 22:
Highlights from your plan
Playa Biesanz ©
Playa Biesanz
Nature & Wildlife Tours
Zipline

1
night
Panama City, Panama

Panama City ©
Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
On the 23rd (Wed), take an in-depth tour of Museo del Canal Interoceanico de Panama and then get to know the fascinating history of Avenida Balboa. Here are some ideas for day two: examine the collection at Biomuseo and then wander the streets of Cinta Costera.

To see ratings, more things to do, maps, and more tourist information, read Panama City itinerary planning app.

You can fly from Manuel Antonio to Panama City in 8 hours. Alternatively, you can drive; or take a bus. The time zone changes from Central Standard Time (CST) to Eastern Standard Time (EST), which is usually a 1 hour difference. September in Panama City sees daily highs of 36°C and lows of 28°C at night. Cap off your sightseeing on the 24th (Thu) early enough to travel to San Andres Island.

Things to do in Panama City

Historic Sites · Neighborhoods · Museums
Find places to stay Sep 22 — 24:
Highlights from your plan
Avenida Balboa ©
Avenida Balboa
Biomuseo ©
Biomuseo
Cinta Costera ©
Cinta Costera

2
nights
San Andres Island, Colombia

San Andres Island ©
The coral San Andres Island boasts a rich colonial history, exotic beaches, and a laidback, tropical lifestyle.
On the 25th (Fri), identify plant and animal life at La Piscinita and then see the vivid underwater world at West View. On your second day here, identify plant and animal life at Cayo El Acuario and then enjoy the sand and surf at Playa de Spratt Bight.

For other places to visit, reviews, traveler tips, and more tourist information, go to the San Andres Island visit app.

Getting from Panama City to San Andres Island by flight takes about 5 hours. In September in San Andres Island, expect temperatures between 36°C during the day and 30°C at night. Finish your sightseeing early on the 26th (Sat) to allow enough time to travel to Cartagena.

Things to do in San Andres Island

Parks · Wildlife · Outdoors
Find places to stay Sep 24 — 26:
Highlights from your plan
Playa de Spratt Bight ©
Playa de Spratt Bight
West View
West View
La Piscinita ©
La Piscinita

3
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Do some cultural sightseeing at Choco Museo and Torre del Reloj. Sanctuary of Saint Peter Claver and Convent of Santa Cruz de la Popa will appeal to history buffs. The adventure continues: get outside with Outdoor Activities, don't miss a visit to Plaza Bolivar, and gain insight at Plaza Santo Domingo.

To find other places to visit, maps, more things to do, and other tourist information, you can read our Cartagena tour itinerary app.

You can fly from San Andres Island to Cartagena in 3.5 hours. September in Cartagena sees daily highs of 38°C and lows of 30°C at night. Wrap up your sightseeing on the 29th (Tue) to allow time to travel to Los Roques National Park.

Things to do in Cartagena

Historic Sites · Wildlife · Outdoors
Find places to stay Sep 26 — 29:
Highlights from your plan
Plaza Santo Domingo ©
Plaza Santo Domingo
Choco Museo ©
Choco Museo
Scuba & Snorkeling

1
night
Los Roques National Park, Venezuela

Los Roques National Park ©
Indulge in a relaxing, tropical vacation in Los Roques National Park, a stunning chain of more than 300 coral islands.
Start off your visit on the 30th (Wed): head off the coast to Cayo De Agua. On the next day, step off the mainland to explore Crasqui.

To find other places to visit, maps, and other tourist information, you can read our Los Roques National Park trip planner.

Fly from Cartagena to Los Roques National Park in 11.5 hours. Traveling from Cartagena to Los Roques National Park, you'll lose 1 hour due to the time zone difference. Finish up your sightseeing early on the 1st (Thu) so you can travel to Quito.

Things to do in Los Roques National Park

Nature · Parks · Outdoors
Find places to stay Sep 30 — Oct 1:
Highlights from your plan
Cayo De Agua ©
Cayo De Agua
Crasqui ©
Crasqui

3
nights
Quito, Ecuador

Quito ©
High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
Discover out-of-the-way places like Casa del Alabado and La Virgen del Panecillo. Visit Quito Old Town and Basilica del Voto Nacional for their historical value. Next up on the itinerary: take an in-depth tour of Museo Templo del Sol Pintor Ortega Maila, make a trip to Mitad Del Mundo, admire the masterpieces at La Capilla Del Hombre, and contemplate in the serene atmosphere at Fundacion Iglesia de la Compania.

To find maps, photos, and tourist information, refer to the Quito trip builder tool.

Traveling by flight from Los Roques National Park to Quito takes 11 hours. Due to the time zone difference, you'll gain 1 hour traveling from Los Roques National Park to Quito. October in Quito sees daily highs of 26°C and lows of 17°C at night. Finish up your sightseeing early on the 4th (Sun) so you can travel to Cusco.

Things to do in Quito

Historic Sites · Museums
Find places to stay Oct 1 — 4:
Highlights from your plan
Casa del Alabado ©
Casa del Alabado
La Virgen del Panecillo ©
La Virgen del Panecillo
Museo Templo del Sol Pintor Ortega Maila ©

4
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Get some historical perspective at Iglesia de la Compania de Jesus and San Blas. Your cultural itinerary includes sights like Santuario Animal de Cochahuasi and Q'enqo. Step out of Cusco to go to Ollantaytambo and see Archaeological Park Ollantaytambo, which is approximately 1h 50 min away. Next up on the itinerary: surround yourself with nature on a nature and wildlife tour, explore the ancient world of Tambomachay, steep yourself in history at Sacred Valley of the Incas, and trot along with a tour on horseback.

To find more things to do, ratings, other places to visit, and tourist information, refer to the Cusco online tour itinerary planner.

Fly from Quito to Cusco in 8 hours. Alternatively, you can drive; or take a bus. Expect slightly colder evenings in Cusco when traveling from Quito in October, with lows around 7°C. Finish your sightseeing early on the 8th (Thu) to allow enough time to travel to Uyuni.

Things to do in Cusco

Historic Sites · Outdoors · Tours

Side Trips

Archaeological Park Ollantaytambo, Sacred Valley of the Incas
Find places to stay Oct 4 — 8:
Highlights from your plan
Archaeological Park Ollantaytambo ©
Archaeological Park Ollantaytambo
Iglesia de la Compania de Jesus ©
Iglesia de la Compania de Jesus
Q'enqo ©
Q'enqo

1
night
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
On the 9th (Fri), see the interesting displays at Train Cemetery. Get ready for a full day of sightseeing on the 10th (Sat): take in the dramatic natural features at Salar de Uyuni and then step off the mainland to explore Isla Incahuasi.

For photos, where to stay, other places to visit, and other tourist information, read our Uyuni trip itinerary website.

You can fly from Cusco to Uyuni in 7 hours. Other options are to drive; or do a combination of bus and taxi. The time zone difference moving from Peru Standard Time (PET) to Bolivia Time (BOT) is 1 hour. When traveling from Cusco in October, plan for much colder days in Uyuni, with highs around 8°C, while nights are about the same with lows around 7°C. Finish up your sightseeing early on the 10th (Sat) so you can travel to San Pedro de Atacama.

Things to do in Uyuni

Nature · Parks · Museums
Find places to stay Oct 8 — 10:
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Train Cemetery ©
Train Cemetery
Isla Incahuasi ©
Isla Incahuasi

3
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Step out of the city life by going to Off-Road Tours and Valle Arcoiris. Do some cultural sightseeing at Museo del Meteorito and Pukara de Quitor. There's still lots to do: get a dose of the wild on a nature and wildlife tour, witness a stunning natural landmark at Termas Banos de Puritama, explore the activities along Lagunas Miscanti y Miniques, and make a trip to Mirador de Kari, Piedra del Coyote.

For where to stay, other places to visit, maps, and more tourist information, read San Pedro de Atacama day trip planning site.

Getting from Uyuni to San Pedro de Atacama by combination of taxi and bus takes about 11.5 hours. Other options: drive; or do a combination of taxi and bus. Traveling from Uyuni in October, you will find days in San Pedro de Atacama are much hotter (28°C), and nights are slightly colder (3°C). Cap off your sightseeing on the 14th (Wed) early enough to travel to San Carlos de Bariloche.

Things to do in San Pedro de Atacama

Parks · Outdoors · Tours
Find places to stay Oct 11 — 14:
Highlights from your plan
Lagunas Miscanti y Miniques ©
Lagunas Miscanti y Miniques
Valle Arcoiris ©
Valle Arcoiris
Off-Road Tours

4
nights
San Carlos de Bariloche, Argentina

San Carlos de Bariloche
Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
Escape the urban bustle at Piedras Blancas and Isla Victoria. Discover out-of-the-way places like Museo del Lago Gutierrez and Chocolates Rapanui. Spend the 18th (Sun) exploring nature at Parque Nacional Nahuel Huapi. The adventure continues: stroll around Parque Nahuelito, get outside with Outdoor Activities, and hit the slopes at Catedral Alta Patagonis.

To see other places to visit, reviews, more things to do, and more tourist information, read our San Carlos de Bariloche trip planner.

Traveling by combination of flight and bus from San Pedro de Atacama to San Carlos de Bariloche takes 13 hours. Alternatively, you can do a combination of bus and flight; or drive. Due to the time zone difference, you'll lose 1 hour traveling from San Pedro de Atacama to San Carlos de Bariloche. Traveling from San Pedro de Atacama in October, you will find days in San Carlos de Bariloche are a bit cooler (17°C), and nights are about the same (1°C). Finish up your sightseeing early on the 19th (Mon) so you can travel to Punta del Este.

Things to do in San Carlos de Bariloche

Parks · Outdoors · Winter Sports
Find places to stay Oct 15 — 19:
Highlights from your plan
Catedral Alta Patagonis
Catedral Alta Patagonis
Museo del Lago Gutierrez ©
Museo del Lago Gutierrez
Nature & Wildlife Tours

2
nights
Punta del Este, Uruguay

Punta del Este ©
With plenty of modern casinos, well-developed beaches, chic restaurants, and upscale hotels, Punta del Este vacations draw visitors from Argentina, Brazil, and beyond.
Start off your visit on the 20th (Tue): make a trip to Cerro San Antonio, kick back and relax at Playa Brava, and then make a trip to Puerto de Punta del Este. Keep things going the next day: examine the collection at Museo Del Mar, then snap pictures at Puente Leonel Viera, and then enjoy the sand and surf at Playa Mansa.

You can plan Punta del Este trip in no time by asking Inspirock to help create your itinerary.

You can fly from San Carlos de Bariloche to Punta del Este in 7 hours. Other options are to drive; or do a combination of bus, train, and ferry. While traveling from San Carlos de Bariloche, expect a bit warmer days and much hotter nights in Punta del Este, ranging from highs of 20°C to lows of 15°C. Finish your sightseeing early on the 21st (Wed) to allow enough time to travel to Ciudad Del Este.

Things to do in Punta del Este

Outdoors · Beaches · Parks

Side Trips

Maldonado, Cerro San Antonio
Find places to stay Oct 19 — 21:
Highlights from your plan
Playa Mansa ©
Playa Mansa
Museo Del Mar ©
Museo Del Mar
Playa Brava ©
Playa Brava

1
night
Ciudad Del Este, Paraguay

Ciudad Del Este ©
The commercial center of eastern Paraguay, busy Ciudad Del Este serves primarily as a shopping destination for Argentines and Brazilians.
On the 22nd (Thu), browse the different shops at Nissei and then make a trip to PRESA DE ITAIPU.

To find other places to visit, traveler tips, maps, and other tourist information, read Ciudad Del Este trip planner.

Getting from Punta del Este to Ciudad Del Este by combination of flight and car takes about 9 hours. Other options: drive; or do a combination of bus and car. Plan for somewhat warmer temperatures traveling from Punta del Este in October, with highs in Ciudad Del Este at 34°C and lows at 20°C. Wrap up your sightseeing on the 22nd (Thu) early enough to travel to Florianopolis.

Things to do in Ciudad Del Este

Shopping
Find places to stay Oct 21 — 22:
Highlights from your plan
Nissei ©
Nissei
PRESA DE ITAIPU ©
PRESA DE ITAIPU

4
nights
Florianopolis, Brazil

Florianopolis ©
Divided between island and mainland, the distinctive city of Florianopolis charms visitors on first arrival with its impressive skyline.
Step out of the city life by going to Itapema Beach and Guarda do Embau Beach. Visit Praia do Rosa and Barra da Lagoa Beach for some beach relaxation. Change things up with these side-trips from Florianopolis: Praia das Laranjeiras (in Balneario Camboriu) and Bombinhas Beach (in Bombinhas). There's lots more to do: take a stroll through Costa da Lagoa, kick back and relax at Lagoinha do Leste, and stroll through Praia Mole.

Inspirock's itinerary builder makes planning a Florianopolis trip simple and quick.

You can do a combination of bus and flight from Ciudad Del Este to Florianopolis in 8 hours. Alternatively, you can drive; or do a combination of car and flight. Traveling from Ciudad Del Este in October, expect nights in Florianopolis to be about the same, around 20°C, while days are a bit cooler, around 28°C. Finish your sightseeing early on the 27th (Tue) so you can travel to Brasilia.

Things to do in Florianopolis

Outdoors · Beaches · Parks

Side Trips

Guarda do Embau Beach, Praia do Rosa, Itapema Beach, Praia das Laranjeiras, Bombinhas Beach
Find places to stay Oct 22 — 27:
Highlights from your plan
Praia do Rosa ©
Praia do Rosa
Guarda do Embau Beach ©
Guarda do Embau Beach
Bombinhas Beach ©
Bombinhas Beach

3
nights
Brasilia, Brazil

Brasilia ©
Although it lacks the cultural flair of Rio de Janeiro and the massive urban sprawl of Sao Paulo, Brasilia holds a fascinating place in the tapestry of Brazil.
On the 28th (Wed), stroll around Parque da Cidade Sarah Kubitschek, then get engrossed in the history at Memorial JK, and then contemplate in the serene atmosphere at Santuario Dom Bosco. On your second day here, admire the landmark architecture of Ermida Dom Bosco, take in the views from Juscelino Kubitschek Bridge, and then admire the landmark architecture of Templo da Boa Vontade.

To find reviews, maps, ratings, and more tourist information, refer to the Brasilia tour planning website.

Traveling by flight from Florianopolis to Brasilia takes 5 hours. Alternatively, you can drive; or take a bus. Traveling from Florianopolis in October, you will find days in Brasilia are a bit warmer (35°C), and nights are about the same (20°C). Finish your sightseeing early on the 30th (Fri) so you can travel back home.

Things to do in Brasilia

Historic Sites · Parks · Museums
Find places to stay Oct 27 — 30:
Highlights from your plan
Santuario Dom Bosco ©
Santuario Dom Bosco
Ermida Dom Bosco ©
Ermida Dom Bosco
Memorial JK ©
Memorial JK

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