27 days in Mexico & Santiago de Cuba Itinerary

27 days in Mexico & Santiago de Cuba Itinerary

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Route & dates

27 days in Mexico & Santiago de Cuba Itinerary

Start: Johannesburg, South Africa
Fly:  23​h 45​min
1
Cancun, Mexico
— 2 nights
+2
Fly + taxi + bus:  6​h
2
San Miguel de Allende, Mexico
— 3 nights
+2
bus + taxi + Fly:  4​h 30​min
3
Puerto Vallarta, Mexico
— 3 nights
Fly:  3​h 15​min
4
Mexico City, Mexico
— 3 nights
Fly:  3​h 15​min
5
Palenque, Mexico
— 2 nights
+4
bus + foot + Fly + foot + bus:  7​h
6
Tulum, Mexico
— 4 nights
Drive:  2​h 30​min
7
Cozumel, Mexico
— 3 nights
Fly:  7​h 45​min
8
Santiago de Cuba, Cuba
— 2 nights
Fly:  29​h
End: Johannesburg, South Africa

2
nights
Cancun, Mexico

Few destinations in Mexico dazzle visitors quite like Cancun, a modern resort town filled with glitzy hotels sitting on picturesque and well-developed Caribbean beaches.
Cancun is known for nightlife, wildlife, adventure, shopping, and beaches. Your plan includes some of its best attractions: browse the different shops at La Isla Shopping Village, delve into the distant past at El Rey Archaeological Zone, indulge in some personalized pampering at some of the best spas, and get outside with Outdoor Activities.

Plan my day in Cancun using traveler tips and tourist information provided by Inspirock.

Johannesburg, South Africa to Cancun is an approximately 24-hour flight. You'll gain 7 hours traveling from Johannesburg to Cancun due to the time zone difference. Plan for somewhat warmer temperatures traveling from Johannesburg in April, with highs in Cancun at 34°C and lows at 27°C. Finish up your sightseeing early on the 14th (Tue) so you can travel to San Miguel de Allende.

Things to do in Cancun

Tours Outdoors Adventure
Find places to stay Apr 11 — 14:
Highlights from your plan
Swim with Dolphins
La Isla Shopping Village ©
La Isla Shopping Village
Zipline

3
nights
San Miguel de Allende, Mexico

A relatively small town in central Mexico, relaxed San Miguel de Allede offers an ideal setting for visitors in search of a bit of history and a great deal of photogenic architecture.
San Miguel de Allende is known for historic sites, shopping, parks, museums, and classes. Your plan includes some of its best attractions: contemplate in the serene atmosphere at Parroquia de San Miguel Arcangel, see the interesting displays at Museo La Esquina, look for gifts at Colors, and don't miss a visit to El Jardin.

For maps, reviews, where to stay, and other tourist information, use the San Miguel de Allende online itinerary planner .

Getting from Cancun to San Miguel de Allende by combination of flight and bus takes about 6 hours. Other options: do a combination of flight, taxi, and bus; or drive. The time zone difference moving from Eastern Standard Time (EST) to Central Standard Time (CST) is minus 1 hour. Traveling from Cancun in April, San Miguel de Allende is much colder at night with lows of 13°C. Finish your sightseeing early on the 17th (Fri) so you can travel to Puerto Vallarta.

Things to do in San Miguel de Allende

Tours Outdoors Parks
Find places to stay Apr 14 — 17:
Highlights from your plan
Horseback Riding Tours
Parroquia de San Miguel Arcangel ©
Parroquia de San Miguel Arcangel
Spas

3
nights
Puerto Vallarta, Mexico

Boasting a coastline made for perfectly framed photographs of romantic sunsets, Puerto Vallarta continuously ranks among the world's top tourist resorts.
Puerto Vallarta is known for wildlife, nightlife, adventure, historic sites, and spas. Your plan includes some of its best attractions: take in the waterfront at Malecon Boardwalk, get to know the fascinating history of Zona Romantica, take in the exciting artwork at Galleria Dante, and head off the coast to Marietas Islands.

To see where to stay, ratings, traveler tips, and more tourist information, read our Puerto Vallarta online attractions planner .

Do a combination of bus, taxi, and flight from San Miguel de Allende to Puerto Vallarta in 4.5 hours. Alternatively, you can do a combination of bus and flight; or drive. Traveling from San Miguel de Allende in April, expect somewhat warmer with lows of 22°C in Puerto Vallarta. Finish your sightseeing early on the 20th (Mon) to allow enough time to travel to Mexico City.

Things to do in Puerto Vallarta

Tours Outdoors Adventure

Side Trip

Marietas Islands
Find places to stay Apr 17 — 20:
Highlights from your plan
Zipline
Malecon Boardwalk ©
Malecon Boardwalk
Marietas Islands ©
Marietas Islands

3
nights
Mexico City, Mexico

Mexico City ©
Breathtakingly large, Mexico City provides a home for almost 9 million people living in nearly 1,700 distinct neighborhoods.
Change things up with a short trip to Zona Arqueológica de Teotihuacan Estacionamiento Puerta 5 in San Juan Teotihuacan (about 1h 15 min away). There's lots more to do: see the interesting displays at Museo Nacional de Antropologia, delve into the distant past at Museo del Templo Mayor, contemplate in the serene atmosphere at Metropolitan Cathedral (Catedral Metropolitana), and explore the world behind art at Palacio de Bellas Artes.

For maps, other places to visit, and tourist information, go to the Mexico City trip planner.

Fly from Puerto Vallarta to Mexico City in 3.5 hours. Alternatively, you can do a combination of flight and bus; or drive. Traveling from Puerto Vallarta in April, plan for slightly colder nights in Mexico City, with lows around 15°C. Finish your sightseeing early on the 23rd (Thu) so you can travel to Palenque.

Things to do in Mexico City

Historic Sites Museums Tours

Side Trip

Zona Arqueológica de Teotihuacan Estacionamiento Puerta 5
Find places to stay Apr 20 — 23:
Highlights from your plan
Museo del Tiempo Tlalpan ©
Museo del Tiempo Tlalpan
Museo Nacional de Antropologia ©
Museo Nacional de Antropologia
Palacio de Bellas Artes ©
Palacio de Bellas Artes

2
nights
Palenque, Mexico

Palenque ©
Palenque remains best known for the nearby ruins of an ancient Mayan city, which probably flourished around the 7th century CE.
Kick off your visit on the 24th (Fri): admire the sheer force of Cascada de Roberto Barrios and then admire the sheer force of La Asuncion. On your second day here, pause for some serene contemplation at Iglesia Santo Domingo, don't miss a visit to Zona Arqueologica de Palenque, and then admire the sheer force of Welib Ja Waterfalls.

To find other places to visit, traveler tips, photos, and more tourist information, read Palenque trip itinerary maker website .

You can fly from Mexico City to Palenque in 3.5 hours. Other options are to do a combination of flight and bus; or drive. Finish your sightseeing early on the 25th (Sat) so you can travel to Tulum.

Things to do in Palenque

Parks Nature Historic Sites
Find places to stay Apr 23 — 25:
Highlights from your plan
Cascada de Roberto Barrios ©
Cascada de Roberto Barrios
Zona Arqueologica de Palenque ©
Zona Arqueologica de Palenque
Iglesia Santo Domingo ©
Iglesia Santo Domingo

4
nights
Tulum, Mexico

Tulum ©
The only Mayan site built to overlook the ocean, Tulum remains a coastal paradise preserving the last vestiges of a pre-Hispanic civilization.
You'll find plenty of places to visit near Tulum: Chichen Itza (Chichen Itza & Temple of the Bearded Man) and Playa del Carmen (Xcaret, Scuba & Snorkeling, & more). And it doesn't end there: explore the ancient world of Tulum Archaeological Site, explore the activities along Casa Cenote, take in panoramic vistas at Tulum Tower, and look for gifts at Kaahal Home Tulum.

To find maps, reviews, more things to do, and tourist information, use the Tulum holiday app .

You can do a combination of bus and flight from Palenque to Tulum in 7 hours. Other options are to do a combination of flight and bus; or drive. Due to the time zone difference, you'll lose 1 hour traveling from Palenque to Tulum. In April, plan for daily highs up to 33°C, and evening lows to 24°C. Cap off your sightseeing on the 29th (Wed) early enough to go by car to Cozumel.

Things to do in Tulum

Tours Outdoors Theme Parks

Side Trips

Playa del Carmen, Chichen Itza
Find places to stay Apr 25 — 29:
Highlights from your plan
Xcaret ©
Xcaret
Tulum Archaeological Site ©
Tulum Archaeological Site
Scuba & Snorkeling

3
nights
Cozumel, Mexico

Thanks to the island's outstanding scuba diving and snorkeling options, Cozumel tourism sector remains a major employer and the main source of income for this Caribbean getaway.
Cozumel is known for wildlife, outdoors, theme parks, adventure, and beaches. Your plan includes some of its best attractions: see some colorful creatures with a scuba or snorkeling tour, make a trip to San Gervasio Mayan Archaeological Site, stroll through Cozumel Pearl Farm, and explore the ancient world of Zona Arqueológica del Cedral.

For photos, where to stay, and more tourist information, read our Cozumel trip itinerary planning site .

Drive from Tulum to Cozumel in 2.5 hours. Expect a daytime high around 33°C in April, and nighttime lows around 24°C. Wrap up your sightseeing on the 2nd (Sat) to allow time to travel to Santiago de Cuba.

Things to do in Cozumel

Wildlife Parks Tours
Find places to stay Apr 29 — May 2:
Highlights from your plan
Scuba & Snorkeling
Discover Mexico Park Cozumel ©
Discover Mexico Park Cozumel
Museo de la Isla de Cozumel ©
Museo de la Isla de Cozumel

2
nights
Santiago de Cuba, Cuba

Santiago de Cuba ©
Santiago de Cuba has taken almost as much influence from Haiti and the Dominican Republic as it has from Havana, distilling a concoction of cultures to create a city with a distinct identity.
Santiago de Cuba is known for historic sites, parks, museums, nightlife, and scenic drive. Your plan includes some of its best attractions: stroll the grounds of Cementerio Santa Ifigenia, view the masterpieces at Galeria Rene Valdes, explore the historical opulence of Castillo de San Pedro de la Roca, and make a trip to Casa Museo Granjita de Siboney.

Take the guesswork out of planning a Santiago de Cuba vacation by using our trip itinerary maker.

Getting from Cozumel to Santiago de Cuba by flight takes about 8 hours. In May, daily temperatures in Santiago de Cuba can reach 35°C, while at night they dip to 26°C. Wrap up your sightseeing on the 5th (Tue) to allow time to travel back home.

Things to do in Santiago de Cuba

Museums Historic Sites Parks

Side Trips

Rancho El Dajao, Cobre
Find places to stay May 2 — 5:
Highlights from your plan
Casa de Diego Velazquez ©
Casa de Diego Velazquez
Cementerio Santa Ifigenia ©
Cementerio Santa Ifigenia
Castillo de San Pedro de la Roca ©

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