22 days in South America Itinerary

22 days in South America Itinerary

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Route & dates

22 days in South America Itinerary

Start: Amsterdam, The Netherlands
Fly:  14 h 30 min
1
Sao Paulo, Brazil
— 2 nights
Fly:  3 h
2
Asuncion, Paraguay
— 2 nights
Bus:  1 h 30 min
3
Ciudad Del Este, Paraguay
— 1 night
Drive + Fly:  3 h
4
Buenos Aires, Argentina
— 4 nights
Fly:  2 h 30 min
5
Punta del Este, Uruguay
— 2 nights
Bus:  2 h
6
Montevideo, Uruguay
— 3 nights
Fly + Bus:  6 h 45 min
7
Gramado, Brazil
— 2 nights
Bus + Fly:  5 h
8
Rio de Janeiro, Brazil
— 5 nights
Fly:  15 h
End: Amsterdam, The Netherlands

2
nights
Sao Paulo, Brazil

Sao Paulo ©
Don't let the city's nickname--"Land of Drizzle"--dampen your spirits during a trip to Sao Paulo.
On the 21st (Sat), indulge your taste buds at Mercado Municipal de São Paulo, walk around Parque Ibirapuera, and then take a stroll through Paulista Avenue. Here are some ideas for day two: see the interesting displays at Museu De Arte Sacra De Sao Paulo, admire the masterpieces at Pinacoteca do Estado de Sao Paulo, and then admire the masterpieces at Museu de Arte de Sao Paulo Assis Chateaubriand - MASP.

For ratings, where to stay, photos, and tourist information, you can read our Sao Paulo trip itinerary builder app .

Amsterdam, The Netherlands to Sao Paulo is an approximately 14.5-hour flight. You can also do a combination of flight and bus; or do a combination of train and flight. You'll gain 4 hours traveling from Amsterdam to Sao Paulo due to the time zone difference. In March, Sao Paulo is much warmer than Amsterdam - with highs of 32°C and lows of 22°C. Finish your sightseeing early on the 22nd (Sun) to allow enough time to travel to Asuncion.

Things to do in Sao Paulo

Museums Shopping Parks
Find places to stay Mar 20 — 22:
Highlights from your plan
Pinacoteca do Estado de Sao Paulo ©
Pinacoteca do Estado de Sao Paulo
Parque Ibirapuera ©
Parque Ibirapuera
Paulista Avenue ©
Paulista Avenue

2
nights
Asuncion, Paraguay

Asuncion ©
Paraguay's capital and economic center, Asuncion ranks among the youngest cities on the continent, with more than half of its residents under 30 years of age.
On the 23rd (Mon), admire the striking features of The National Pantheon of Heroes and Oratory of the Virgin Our Lady Saint Mary of the Asuncion, explore the galleries of Casa de la Independencia, and then get a sense of history and politics at Palacio de López. Get ready for a full day of sightseeing on the next day: explore the world behind art at Museo Etnografico Andres Barbero, get to know the resident critters at Botanical Garden and Zoo (Jardin Botanico y Zoologico), and then head outdoors with Lago Ypacarai.

For other places to visit, maps, more things to do, and other tourist information, use the Asuncion online visit planner .

Traveling by flight from Sao Paulo to Asuncion takes 3 hours. Alternatively, you can drive; or take a bus. The time zone difference when traveling from Sao Paulo to Asuncion is minus 1 hour. While traveling from Sao Paulo, expect a bit warmer days and about the same nights in Asuncion, ranging from highs of 36°C to lows of 24°C. Finish your sightseeing early on the 24th (Tue) to allow enough time to travel to Ciudad Del Este.

Things to do in Asuncion

Museums Historic Sites Parks

Side Trip

Lago Ypacarai
Find places to stay Mar 22 — 24:
Highlights from your plan
Casa de la Independencia ©
Casa de la Independencia
Museo Etnografico Andres Barbero ©
Museo Etnografico Andres Barbero
Palacio de López ©
Palacio de López

1
night
Ciudad Del Este, Paraguay

Ciudad Del Este ©
The commercial center of eastern Paraguay, busy Ciudad Del Este serves primarily as a shopping destination for Argentines and Brazilians.
Kick off your visit on the 25th (Wed): have some family-friendly fun at Museo Planet 3D, get outside with Snow Park, and then take in the dramatic scenery at Saltos del Monday.

To see ratings, where to stay, other places to visit, and tourist information, read Ciudad Del Este travel itinerary planner.

Do a combination of flight and taxi from Asuncion to Ciudad Del Este in 1.5 hours. Alternatively, you can drive; or take a bus. The time zone difference when traveling from Asuncion to Ciudad Del Este is 1 hour. In March, daily temperatures in Ciudad Del Este can reach 34°C, while at night they dip to 22°C. Finish up your sightseeing early on the 25th (Wed) so you can travel to Buenos Aires.

Things to do in Ciudad Del Este

Fun & Games Parks Nature

Side Trip

Saltos del Monday
Find places to stay Mar 24 — 25:
Highlights from your plan
Museo Planet 3D ©
Museo Planet 3D
Saltos del Monday ©
Saltos del Monday
Snow Park ©
Snow Park

4
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Buenos Aires is known for historic sites, nightlife, and parks. Your plan includes some of its best attractions: take in nature's colorful creations at Parque 3 de Febrero, get engrossed in the history at El Zanjon de Granados, ponder the world of politics at Casa Rosada, and admire the masterpieces at Museo Nacional de Bellas Artes.

To see maps, photos, and other tourist information, read Buenos Aires travel route planning site .

Getting from Ciudad Del Este to Buenos Aires by combination of car and flight takes about 3 hours. Other options: fly; or drive. Traveling from Ciudad Del Este in March, you will find days in Buenos Aires are a bit cooler (29°C), and nights are about the same (20°C). Finish your sightseeing early on the 29th (Sun) to allow enough time to travel to Punta del Este.

Things to do in Buenos Aires

Museums Shopping Neighborhoods
Find places to stay Mar 25 — 29:
Highlights from your plan
Museo Nacional de Bellas Artes ©
Museo Nacional de Bellas Artes
Parque 3 de Febrero ©
Parque 3 de Febrero
Cemiterio de Recoleta ©
Cemiterio de Recoleta

2
nights
Punta del Este, Uruguay

Punta del Este ©
With plenty of modern casinos, well-developed beaches, chic restaurants, and upscale hotels, Punta del Este vacations draw visitors from Argentina, Brazil, and beyond.
Start off your visit on the 30th (Mon): admire the landmark architecture of Casapueblo, kick back and relax at Playa Punta Ballena, then explore the world behind art at Museo – Taller de Casapueblo, then make a trip to The Fingers of Punta del Este, and finally take in the views from Puente Leonel Viera. Keep things going the next day: enjoy the sand and surf at Playa Punta Colorada, then get great views at Mirador Punta Ballena, and then kick back and relax at Playa Montoya.

To see more things to do, maps, ratings, and other tourist information, read Punta del Este day trip planning website .

Getting from Buenos Aires to Punta del Este by flight takes about 2.5 hours. Other options: do a combination of flight and bus; or do a combination of ferry and taxi. In March in Punta del Este, expect temperatures between 27°C during the day and 21°C at night. Finish up your sightseeing early on the 31st (Tue) so you can catch the bus to Montevideo.

Things to do in Punta del Este

Beaches Parks Outdoors

Side Trips

Maldonado, Playa Punta Colorada
Find places to stay Mar 29 — 31:
Highlights from your plan
Playa Punta Ballena ©
Playa Punta Ballena
Museo – Taller de Casapueblo ©
Museo – Taller de Casapueblo
Mirador Punta Ballena ©
Mirador Punta Ballena

3
nights
Montevideo, Uruguay

Montevideo ©
With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
Step out of Montevideo to go to Canelones and see Pizzorno Family Estates, which is approximately 44 minutes away. Next up on the itinerary: don't miss a visit to Plaza Independencia, take a stroll through Pocitos, explore the world behind art at Palacio Taranco, and take in the pleasant sights at Rambla de Montevideo.

To see ratings, reviews, more things to do, and tourist information, read Montevideo online tour planner .

You can take a bus from Punta del Este to Montevideo in 2 hours. Alternatively, you can drive. Traveling from Punta del Este in March, Montevideo is little chillier at night with lows of 17°C. Finish up your sightseeing early on the 3rd (Fri) so you can travel to Gramado.

Things to do in Montevideo

Neighborhoods Wineries Museums

Side Trip

Pizzorno Family Estates
Find places to stay Mar 31 — Apr 3:
Highlights from your plan
Pizzorno Family Estates ©
Pizzorno Family Estates
Plaza Independencia ©
Plaza Independencia
Pocitos ©
Pocitos

2
nights
Gramado, Brazil

Gramado ©
Surrounded by impressive mountain scenery in the state of Rio Grande do Sul, the small city of Gramado charms visitors with its alpine European-style architecture and blossoming flowers.
Kick off your visit on the 4th (Sat): admire the majestic nature at Parque Estadual do Caracol, take in the architecture and atmosphere at Paroquia Nossa Senhora de Lourdes, then stroll around Mini Mundo, and finally pause for some serene contemplation at Igreja Matriz Sao Pedro Apostolo. Get ready for a full day of sightseeing on the next day: get in on the family fun at Snowland, contemplate the waterfront views at Lago Negro, then learn about winemaking at Casa Seganfredo, and finally make a trip to Caro Watson Escape Game.

To see traveler tips, where to stay, reviews, and other tourist information, refer to the Gramado day trip website .

Traveling by combination of flight and bus from Montevideo to Gramado takes 7 hours. Alternatively, you can do a combination of flight and taxi; or drive. Wrap up your sightseeing on the 5th (Sun) to allow time to travel to Rio de Janeiro.

Things to do in Gramado

Parks Nature Historic Sites

Side Trip

Canela
Find places to stay Apr 3 — 5:
Highlights from your plan
Lago Negro ©
Lago Negro
Mini Mundo ©
Mini Mundo
Snowland ©
Snowland

5
nights
Rio de Janeiro, Brazil

Rio de Janeiro ©
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
Rio de Janeiro is known for beaches, nightlife, and museums. Your plan includes some of its best attractions: pause for some photo ops at Corcovado - Christ the Redeemer, take your sightseeing to a higher altitude at Pedra Bonita, tour the pleasant surroundings at Praia de Ipanema, and kick back and relax at Pedra do Arpoador.

For traveler tips, other places to visit, where to stay, and other tourist information, use the Rio de Janeiro trip builder app .

You can do a combination of bus and flight from Gramado to Rio de Janeiro in 5 hours. Other options are to drive; or take a bus. April in Rio de Janeiro sees daily highs of 33°C and lows of 26°C at night. Wrap up your sightseeing on the 10th (Fri) to allow time to travel back home.

Things to do in Rio de Janeiro

Parks Beaches Outdoors
Find places to stay Apr 5 — 10:
Highlights from your plan
Corcovado - Christ the Redeemer ©
Corcovado - Christ the Redeemer
Copacabana Beach ©
Copacabana Beach
Praia de Ipanema
Praia de Ipanema

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