21 days in South America Itinerary

21 days in South America Itinerary

Created using Inspirock South America itinerary planner

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Route & dates

21 days in South America Itinerary

Start: Melbourne, Australia
Fly:  17 h 30 min
1
Santiago, Chile
— 2 nights
+4
Fly + Taxi + Bus + Foot + Train:  9 h 45 min
2
Machu Picchu, Peru
— 1 night
+2
Train + Foot + Bus:  3 h 15 min
3
Cusco, Peru
— 2 nights
Fly:  14 h
4
Manaus, Brazil
— 1 day
Fly:  8 h 15 min
5
Fernando de Noronha, Brazil
— 3 nights
Fly:  7 h
6
Rio de Janeiro, Brazil
— 3 nights
Fly:  2 h 30 min
7
Foz do Iguacu, Brazil
— 1 night
Shuttle + Fly:  4 h 30 min
8
Buenos Aires, Argentina
— 4 nights
Fly:  21 h 45 min
End: Melbourne, Australia

2
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Get some cultural insight at La Chascona and Museo Chileno de Arte Precolombino. Next up on the itinerary: take your sightseeing to a higher altitude at San Cristóbal Hill, take in panoramic vistas at Sky Costanera, go for a walk through Plaza de Armas, and stroll around Cerro Santa Lucia.

Plan trip to Santiago with our itinerary maker to find out where to go and what to do.

Melbourne, Australia to Santiago is an approximately 17.5-hour flight. You can also do a combination of bus and flight; or do a combination of flight and car. The time zone difference moving from Australian Eastern Standard Time (Victoria) (AEST) to Chile Time (CLT) is minus 14 hours. Cap off your sightseeing on the 9th (Mon) early enough to travel to Machu Picchu.

Things to do in Santiago

Parks Museums Nature
Find places to stay Nov 7 — 9:
Highlights from your plan
San Cristóbal Hill ©
San Cristóbal Hill
La Chascona ©
La Chascona
Museo Chileno de Arte Precolombino ©
Museo Chileno de Arte Precolombino

1
night
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Start off your visit on the 10th (Tue): make a trip to Intipuncu and then delve into the distant past at Winay Wayna. Get ready for a full day of sightseeing on the 11th (Wed): contemplate the long history of Santuario Historico de Machu Picchu and then take in nature's colorful creations at Los Jardines de Mandor.

Discover how to plan a Machu Picchu trip in just a few steps with Inspirock's itinerary builder.

Traveling by combination of flight, bus, and train from Santiago to Machu Picchu takes 10 hours. Alternatively, you can do a combination of flight and car; or drive. Due to the time zone difference, you'll gain 1 hour traveling from Santiago to Machu Picchu. Finish up your sightseeing early on the 11th (Wed) so you can travel to Cusco.

Things to do in Machu Picchu

Historic Sites Parks Wildlife
Find places to stay Nov 9 — 11:
Highlights from your plan
Santuario Historico de Machu Picchu ©
Santuario Historico de Machu Picchu
Winay Wayna ©
Winay Wayna
Intipuncu ©
Intipuncu

2
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
On the 12th (Thu), trek along exploor, steep yourself in history at Plaza de Armas, then contemplate the long history of Sacsayhuaman, and finally admire the masterpieces at Museo de Arte Precolombino. On the next day, delve into the distant past at Tambomachay, then steep yourself in history at Tipon, then contemplate in the serene atmosphere at Museo de Vida Monastica - Monasterio de Santa Catalina del Cusco, and finally take in the architecture and atmosphere at Iglesia De Santo Domingo.

To find photos, where to stay, reviews, and tourist information, refer to the Cusco trip maker website .

You can do a combination of train and bus from Machu Picchu to Cusco in 3.5 hours. Alternatively, you can take a train; or drive. In November, daytime highs in Cusco are 26°C, while nighttime lows are 8°C. Cap off your sightseeing on the 13th (Fri) early enough to travel to Manaus.

Things to do in Cusco

Historic Sites Museums Outdoors
Find places to stay Nov 11 — 13:
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Plaza de Armas ©
Plaza de Armas
Iglesia De Santo Domingo ©
Iglesia De Santo Domingo

1
day
Manaus, Brazil

Manaus ©
It's hard not to get excited when planning a trip to Manaus, capital of the state of Amazonas, and the largest city on the mighty Amazon River.
On the 14th (Sat), pause for some serene contemplation at Paroquia Nossa Senhora de Fatima and then explore the activities along Meeting of Waters.

Discover how to plan a Manaus trip in just a few steps with Inspirock's itinerary builder.

Traveling by flight from Cusco to Manaus takes 14 hours. Alternatively, you can drive. The time zone changes from Peru Time (PET) to Amazon Time (AMT), which is usually a 1 hour difference. Expect a bit warmer weather when traveling from Cusco in November: highs in Manaus hover around 36°C, while lows dip to 28°C. Wrap up your sightseeing on the 14th (Sat) early enough to travel to Fernando de Noronha.

Things to do in Manaus

Nature Parks Historic Sites
Find places to stay Nov 14 — 15:
Highlights from your plan
Meeting of Waters ©
Meeting of Waters
Paroquia Nossa Senhora de Fatima ©
Paroquia Nossa Senhora de Fatima

3
nights
Fernando de Noronha, Brazil

Fernando de Noronha ©
With 21 lush islands scattered among pristine waters in the Atlantic Ocean, a Fernando de Noronha holiday is well worth the effort it takes to get there.
Get outdoors at Baia do Sancho and Shark Diving. The adventure continues: get outside with Baia dos Porcos, contemplate the waterfront views at Buraco do Galego, kick back and relax at Praia do Cacimba do Padre, and see the sky in a new way at Aulas de Energia – Espaco Usina Solar Fernando de Noronha.

To find traveler tips, other places to visit, and more tourist information, you can read our Fernando de Noronha travel route planner.

You can fly from Manaus to Fernando de Noronha in 8.5 hours. You'll lose 2 hours traveling from Manaus to Fernando de Noronha due to the time zone difference. In November, plan for daily highs up to 35°C, and evening lows to 29°C. Finish your sightseeing early on the 18th (Wed) so you can fly to Rio de Janeiro.

Things to do in Fernando de Noronha

Outdoors Parks Tours
Find places to stay Nov 14 — 18:
Highlights from your plan
Baia do Sancho ©
Baia do Sancho
Baia dos Porcos ©
Baia dos Porcos
Morro dois Irmaos ©
Morro dois Irmaos

3
nights
Rio de Janeiro, Brazil

Rio de Janeiro ©
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
Visit Ilha Fiscal and Parque Lage for their historical value. Get outdoors at Copacabana Beach and Parque Nacional Tijuca. The adventure continues: stroll through Praia de Ipanema, don't miss a visit to Corcovado - Christ the Redeemer, kick back and relax at Leblon Beach, and take in nature's colorful creations at Jardim Botânico do Rio de Janeiro.

To find other places to visit, photos, more things to do, and tourist information, use the Rio de Janeiro online road trip planner .

You can fly from Fernando de Noronha to Rio de Janeiro in 7 hours. Traveling from Fernando de Noronha to Rio de Janeiro, you'll gain 1 hour due to the time zone difference. Traveling from Fernando de Noronha in November, you can expect nighttime temperatures to be slightly colder in Rio de Janeiro, with lows of 25°C. Wrap up your sightseeing on the 21st (Sat) to allow time to travel to Foz do Iguacu.

Things to do in Rio de Janeiro

Parks Outdoors Beaches
Find places to stay Nov 18 — 21:
Highlights from your plan
Copacabana Beach ©
Copacabana Beach
Praia de Ipanema
Praia de Ipanema
Corcovado - Christ the Redeemer ©
Corcovado - Christ the Redeemer

1
night
Foz do Iguacu, Brazil

Foz do Iguacu ©
A gateway to the world-renowned Iguacu Falls, which spectacularly divide Brazil and Argentina, the modern, high-rise city of Foz do Iguacu can't help but play second fiddle to the natural wonder in its vicinity.
Kick off your visit on the 22nd (Sun): contemplate in the serene atmosphere at Buddhist Temple and then admire the sheer force of Iguazu Falls.

Ask Inspirock to suggest an itinerary and make planning a trip to Foz do Iguacu fast, fun, and easy.

Traveling by flight from Rio de Janeiro to Foz do Iguacu takes 2.5 hours. Alternatively, you can drive; or take a bus. Traveling from Rio de Janeiro in November, plan for a bit cooler nights in Foz do Iguacu, with lows around 22°C. Wrap up your sightseeing on the 22nd (Sun) to allow time to travel to Buenos Aires.

Things to do in Foz do Iguacu

Nature Parks Historic Sites
Find places to stay Nov 21 — 22:
Highlights from your plan
Iguazu Falls ©
Iguazu Falls
Buddhist Temple ©
Buddhist Temple

4
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Cemiterio de Recoleta and Puerto Madero are good opportunities to explore the local culture. Get some historical perspective at Plaza de Mayo and Calle Defensa. There's much more to do: admire the natural beauty at Parque 3 de Febrero, admire the masterpieces at Museo Nacional de Bellas Artes, admire the striking features of El Ateneo Grand Splendid, and get a sense of history and politics at Casa Rosada.

For photos, where to stay, reviews, and more tourist information, read Buenos Aires holiday builder app .

Traveling by combination of shuttle and flight from Foz do Iguacu to Buenos Aires takes 4.5 hours. Alternatively, you can do a combination of car and flight; or drive. When traveling from Foz do Iguacu in November, plan for little chillier days and about the same nights in Buenos Aires: temperatures range from 28°C by day to 19°C at night. You'll have a few hours on the 26th (Thu) to wrap things up before traveling home.

Things to do in Buenos Aires

Historic Sites Neighborhoods Museums
Find places to stay Nov 22 — 26:
Highlights from your plan
Cemiterio de Recoleta ©
Cemiterio de Recoleta
Parque 3 de Febrero ©
Parque 3 de Febrero
Plaza de Mayo ©
Plaza de Mayo

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